The museum displays a series of temporary exhibitions devoted to the art and cultural history of the Charmey region.

The Musée de Charmey has been developing its approach to the applied arts since 1991. Its positioning has been refined, particularly in the field of paper art, thanks to its Triennale Internationale du Papier (International Paper Triennial).

A permanent exhibition displays the Chartreuse de la Valsainte. It is set up around a hermitage that once belonged to the convent. At the same time, this space gives an account of the history of the Chartreuse as well as the spiritual sphere so characteristic of the Cartesian brothers.